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Skincare in your 40s: firmness, lines and a routine that works

In your 40s, firmness and hydration take centre stage. Here's how to adapt your routine.

5 min read · Updated September 27, 2026
Key takeaways
  • Loss of firmness becomes more noticeable in the 40s.
  • Skin often gets drier; upgrade your moisturiser.
  • Peptides plus optional retinol plus SPF is a proven structure.

What changes

  • The jawline and cheeks can look less defined.
  • Expression lines become more set.
  • Skin may feel drier and look duller.

Your routine

MorningNight
CleanseGentleGentle / double
TreatDOSEDOSE (+ retinol 2–4x a week)
MoisturiseLight to mediumRicher
ProtectSPF 30+–

Focus areas

Pay extra attention to the jawline and forehead. See loss of firmness along the jawline and forehead lines.

FAQ

What's the best serum for your 40s?

A multi-peptide serum is a strong, gentle choice for firmness and fine lines.

Can I combine peptides and retinol in my 40s?

Yes. Use DOSE first, then retinol at night a few times a week.

Should I change my moisturiser?

If your skin feels drier, move to a richer formula, especially at night.

This article is for general information only and isn't medical advice. DOSE is a cosmetic product and is not intended to diagnose, treat, cure or prevent any disease. Individual results vary.