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How to use copper peptide serum: the simple AM and PM routine

Three steps, thirty seconds, twice a day. Here's how to get the most from your copper peptide serum.

5 min read · Updated September 27, 2026
Key takeaways
  • Apply 3–4 drops to clean, dry skin, morning and night.
  • Press it in; don't rub or tug.
  • Keep vitamin C and strong acids for a different time of day.
  • Always finish your morning routine with SPF.

Your morning routine

  1. CleanseUse a gentle cleanser, or just water if your skin is dry. Pat dry.
  2. Copper peptide serumPress 3–4 drops of DOSE into your face.
  3. Moisturise (optional)Add a simple moisturiser if your skin feels dry.
  4. SPFFinish with broad-spectrum SPF 30 or higher, every day.

Your evening routine

  1. CleanseRemove SPF and makeup. Double cleanse if you wear heavy makeup.
  2. Copper peptide serumPress in 3–4 drops.
  3. Retinol (optional)If you use retinol, apply it after DOSE has absorbed, or on alternate nights.
  4. MoisturiseSeal everything in with your usual moisturiser.

How many drops?

3–4 drops covers your whole face. More isn't better: it won't speed up results, it just empties the bottle faster. One 38 mL bottle lasts about 30 days at this rate.

Common mistakes

  • Mixing it with vitamin C in the same step. Copper can make vitamin C less effective. Use vitamin C in the morning and DOSE at night, or vice versa. See copper peptides and vitamin C.
  • Layering it right after strong acids. Low-pH exfoliants can affect how peptides perform. Use acids at a different time or on different days.
  • Giving up after two weeks. Firmness and fine lines take 6–8 weeks to show. See the results timeline.
  • Skipping SPF. Sun exposure undoes a lot of good skincare. Daily SPF protects your results.

Where it goes in your routine

Apply thinnest to thickest: toner or essence, then DOSE, then heavier creams and oils, then SPF in the morning.

FAQ

Should I use copper peptides morning or night?

Both. Twice a day gives the best results. If you use vitamin C in the morning, you can use DOSE at night only, or apply it at a different time from your vitamin C.

Do I apply copper peptide serum before or after moisturiser?

Before. Serums go on clean skin, then moisturiser on top.

Can I use copper peptides around my eyes?

You can apply it gently around the eye area, avoiding the eyes themselves and the lash line.

This article is for general information only and isn't medical advice. DOSE is a cosmetic product and is not intended to diagnose, treat, cure or prevent any disease. Individual results vary.